NSF Calls for Examinations of Emergent Networks as Part of Understanding the Rules of Life “Big Idea”

Nicolle Rager Fuller, National Science Foundation

The biological world is interconnected by complex networks. What are the rules that control these networks? How are the interactions altered by environments? Are the rules similar across all biological scales? How can an understanding of such roles be harnessed to benefit society?

The new Understanding the Rules of Life: Emergent Networks (URoL:EN) solicitation encourages convergent, cross-disciplinary research – including the biological sciences – to examine such rules, the outcomes of these interactions, and to aid in the prediction of emergent properties. The program also seeks to train STEM practitioners to contribute to this area of convergent research. Proposals under the solicitation should be submitted by May 10, 2021.

As part of the Understanding the Rules of Life: Predicting Phenotype, one of ten “Big Ideas” NSF-wide, this new solicitation builds on previous URoL programs to help increase knowledge and the ability to predict an organism’s observable characteristics—its phenotype—from its genotype.

Understanding the mechanisms at play in the interconnections between living organisms and their environments, across every biological scale, will provide vital insight into grand biological challenges, help advance biotechnology to spur the US bioeconomy, and aid in solving some of society’s issues, including the growing impacts of infectious disease and climate change.

Investigators from across the biological sciences are encouraged to submit proposals in concert with researchers in other disciplines, including the mathematical and physical sciences, geosciences, computer and information sciences, engineering, and behavioral and social sciences.

Directorates from across NSF will be holding a virtual office hour on March 11 beginning at 2:00pm Eastern to answer questions on the solicitation. Register in advance for this webinar: https://nsf.zoomgov.com/webinar/register/WN_kP23L5ymTFKw5EVCqBFcCQ.

For full details and guidance on award types, amounts and other questions, see Understanding the Rules of Life: Emergent Networks (URoL:EN).

NSF Announces Call for Center for Advancement and Synthesis of Open Environmental Data and Sciences

NSF has released a new solicitation for a Center for Advancement and Synthesis of Open Environmental Data and Sciences (NSF 21-549). Letters of Intent for the solicitation are due on April 1, 2021

Exemplifying open and team science, the Center will be fueled by open and freely available biological and other environmental data to catalyze novel scientific questions in environmental biology through the use of data-intensive approaches, research networks, and training in the accession, management, analysis, visualization, and synthesis of large data sets.

The Center will provide vision for speeding discovery through the increased use of large, publicly accessible datasets – such as those provided by the National Ecological Observatory Network (NEON), Integrated Digitized Biocollections (iDigBio), the LTER network, Global Biodiversity Information Facility (GBIF), and others – to address biological research questions through collaborations with scientists in other related disciplines, as well as key questions that emerge at interfaces between biology, informatics, and a breadth of environmental sciences.

It also will foster the development of generalizable cyberinfrastructure solutions and community-driven standards for software, data, and metadata that support open and team science, and role-modeling best practices.

The Center will be a leader in diversifying the data-intensive environmental science workforce across demographic, geographic, institutional, and disciplinary dimensions and will further enable data-driven discovery through immersive education and training experiences to provide the advanced skills needed to maximize the scientific potential of large volumes of available open data.

For more information on the solicitation, including a list of cognizant Program Officers, please visit the program page: https://www.nsf.gov/funding/pgm_summ.jsp?pims_id=505829&org=NSF&sel_org=NSF&from=fund.

From the AD: BIO “No-Deadline” Solicitations Migrating to Research.gov

As part of NSF’s ongoing efforts to innovate and migrate proposal preparation and submission capabilities from FastLane to Research.gov (see Important Notice No. 147), the Directorate for Biological Sciences (BIO) has announced that proposal submissions for our “no-deadline” programs will migrate to Research.gov beginning with revised solicitations to be released in the near future. This change was announced in a Dear Colleague Letter (NSF 20-129) released today and is the first phase of a migration of all NSF solicitations to Research.gov.

Specifically, the following programs will have new solicitations published in the coming weeks at which point investigators should begin submitting proposals through Research.gov. There will be a grace period of 90-days from the date on which the new solicitations are published during which proposals can still be submitted through FastLane. After the 90-day period, the new solicitations will no longer be available in FastLane and any new proposals must be submitted through Research.Gov (or Grants.Gov).

The programs whose solicitations will migrate from FastLane to Research.gov are:

Research.gov improves the user experience while also reducing administrative burden. The system is also flexible enough to meet both users’ changing needs and emerging government requirements. A significant fraction of proposals is already being submitted through Research.gov and investigators report it to be intuitive to use. We do not anticipate that the change to Research.gov will have significant impacts on the submission process. This migration will not affect the merit review process in any way.

To support the community through this migration, technical support and FAQs and videos on proposal submission through Research.gov are available. In addition, we are offering a series of BIO-wide virtual office hours during which you can ask questions of BIO Program Officers.

The virtual office hours will occur on Monday, October 19 at 11 a.m. EDT; Tuesday October 20 at 10 a.m. EDT; Wednesday, October 21 at 1 p.m. EDT; and Thursday, October 22 at 3 p.m. EDT. Members of the community can register for these sessions via NSF.gov.

Finally, if you have any immediate questions please reach out to BIOnodeadline@nsf.gov, which is monitored by Program Officers from across BIO.

Sincerely,

Image of the signature of Dr. Joanne Tornow, Assistant Director for Biological Sciences

Joanne S. Tornow, Ph.D.

Assistant Director

Analyzing the Impact of No Deadlines

As you may know, as announced in FY 2018, most programs across the Directorate for Biological Sciences (BIO) had no deadline in FY 2019, a change from previous years. BIO, with the help of a subcommittee of the BIO Advisory Committee, has analyzed proposal data* from FY 2018 and FY 2019 and provided a review of the impact of that change on proposal submissions, funding rates, and more. I’d like to thank that group for their work and share some of the analysis.

The biggest takeaways are – as shown in the chart below – the number of proposals received in FY 2019 was less than in FY 2018, and the funding rate increased in FY 2019 compared to FY 2018. Specifically, In FY 2018 the funding rate across BIO was 21.0% and in FY 2019 it rose to 28.1%.

A chart depicting the change in funding rates and proposal submissions within BIO between FY 2018 and FY 2019.We saw no substantial impact on gender, race, or ethnicity of submitters (PIs or co-PIs on proposal submissions). However, we have seen an increase in the number of individuals who do not provide these data. Similarly, a significant number of co-PIs do not report the year of their highest degree. We are actively monitoring this trend and encourage submitters to provide this information as it helps us better understand the biological sciences community and those seeking funding from BIO.

Lastly, there was a slight shift to shorter periods between submission and funding decision in FY 2019 as compared to FY 2018. There were, however, external circumstances that could have affected this outcome, including the lapse in appropriations. Future data will enlighten our interpretation of the trends in these and other metrics.

BIO will continue to monitor these metrics and others moving forward to measure the impact of the no-deadline policy over time.

*Data includes externally reviewed proposals in core and special programs across all BIO Divisions. It does not include internally reviewed proposals such as RAPIDs, EAGERs, RAISEs, supplements, or conferences, nor does it include human resource proposals such as Fellowships. The unit measured is proposals, which counts single proposal and collaborative proposals as individual units.

Reintegrating Biology Workshop Series Outcomes

The BIO Directorate considers integrative approaches to understanding life’s key innovations as essential for understanding the full diversity of mechanisms regulating fundamental biological processes.

The Reintegrating Biology series of workshops (https://www.nsf.gov/awardsearch/showAward?AWD_ID=1940791&HistoricalAwards=false) included a combination of virtual and in-person events and provided a venue for the broader biological community to discuss the opportunities and challenges for integrating across the biological sub-disciplines. As part of this series of workshops, a total of 318 researchers participated in four concurrent jumpstart meetings in Atlanta, Austin, San Diego and virtually during December 4-6, 2019.  Participants collaborated on a series of vision papers describing what could be accomplished by reintegrating across the subdisciplines of biology, and some of the obstacles preventing such a reintegration from happening. So far, 60 vision papers have been received and can be viewed at: https://reintegratingbiology.org/vision-papers/. Other vision papers have already been submitted for publication. The next Reintegrating Biology event will be a virtual Microlab on January 16 where participants from the four jumpstart meetings will discuss similar themes that emerged during the different events.

NSF would like to thank the participants of the four jumpstart meetings and the broader biological research community for helping make the series of reintegrating biology workshops such a success. These discussions will inform both current integrative biology funding opportunities such as the Rules of Life track in each of the divisional solicitations and the Biology Integration Institutes program (https://www.nsf.gov/funding/pgm_summ.jsp?pims_id=505684&org=BIO&from=home), as well as future activities.

From the AD: Save the Date for BIO’s 2020 Distinguished Lecture Series

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Dear Colleagues,

Please join the Directorate for Biological Sciences (BIO) for the 2020 Distinguished Lecture Series.

BIO’s Distinguished Lecture Series brings eminent researchers to NSF Headquarters in Alexandria, Virginia to speak to BIO scientists, other scientists in the agency, staff members, and a broader Washington-area audience about their research.

Below is more information about the 2020 Distinguished Lecture Series Speakers. Refer to BIO’s homepage for updated information as the lecture dates get closer.

If you wish to attend in person at NSF Headquarters (2415 Eisenhower Ave, Alexandria, VA 22314), please contact Nick Hunt (jamhunt@nsf.gov). Advance sign-up requests are required, and guidelines for visiting NSF are at https://www.nsf.gov/about/visit/

I hope you will be able to attend what are sure to be stimulating and thought-provoking lectures.

Sincerely,

Image of the signature of Dr. Joanne Tornow, Assistant Director for Biological Sciences

Joanne Tornow, PhD
Assistant Director for Biological Sciences

 

BIO’s 2020 Distinguished Lecture Series

Image of Dr. Michael Lynch Dr. Michael Lynch

Biodesign Center for Mechanisms of Evolution

Arizona State University

January 22

11-12pm

E3410

Image of Dr. David Micklos Dr. David Micklos

Dolan DNA Learning Center

Cold Spring Harbor Laboratory

March 5

3-4pm

E3410

Image of Dr. Jef Boeke Dr. Jef Boeke

Institute for Systems Genetics

New York University Langone Medical Center

May 21

11-12pm

E3410

Image of Dr. Hopi Hoekstra Dr. Hopi Hoekstra

Howard Hughes Medical Institute

Harvard University

September 24

11-12pm

TBA

 

From the AD: Remembering Dr. Mary Clutter

Image of the world with "NSF" lettering in white.

Dear Colleagues,

I am deeply saddened to inform you of the passing of Dr. Mary Clutter.

 

Image of Dr. Mary Clutter
Dr. Mary Clutter Image credit: National Science Foundation

Dr. Clutter served as the Assistant Director (AD) for the Directorate for Biological Sciences (BIO) from 1992 to 2005, during which time she served two stints as acting Deputy Director for NSF.  Prior to that, she served as Division Director for Cellular Biosciences in what was previously the Directorate for Biology, Behavioral, and Social Sciences (BBS), as Science Advisor in the Office of the Director from 1985 to 1987, and as a Program Director starting in the 1970s.  She passed away on Sunday, December 8, 2019.

 

Dr. Clutter was a native of Pennsylvania and attended Allegheny College, where she obtained an undergraduate degree in biology.  She later earned her masters and doctorate degrees from the University of Pittsburgh.  She joined NSF as a rotator from Yale University and subsequently was appointed permanently.

Dr. Clutter was always about science first.  Her prescient view of 21st Century Biology predicted it to be integrative from the molecule to the environment, interdisciplinary across all disciplines, driven by a revolution in genomics and computational biology.  She championed plant biology and genomics, advocated for the creation of the National Ecological Observatory Network (NEON), and fostered innovative funding mechanisms within BIO (e.g., Research Coordination Networks and Graduate Research Traineeships) that were subsequently embraced agency-wide.  Furthermore, her commitment to advancing women in academe, in science, and at the NSF was a major hallmark of her time as AD for BIO.  Most notable was her policy memo that prohibited BIO funding of workshops and conferences that did not include women among the presenters, a courageous stance that was noted at the time by the Washington Post.  Dr. Clutter is also credited with the second largest reorganization within NSF in 1992 that resulted in the creation of the Directorates for Biological Sciences and Social, Behavior and Economic Sciences.

Dr. Mary Clutter leaves behind a vibrant legacy that will live on in the memories of her NSF colleagues. We are forever grateful for her service, dedication, and visionary leadership.

Sincerely,
Image of the signature of Dr. Joanne Tornow, Assistant Director for Biological Sciences
Joanne Tornow, PhD
Assistant Director for Biological Sciences

 

From The AD: New Funding Opportunities for Understanding the Rules of Life

Image of the world with "NSF" lettering in white.

Dear Colleagues,

BIO is excited to announce to the biological sciences community two new funding opportunities under the Understanding the Rules of Life (URoL) Big Idea: 1) Epigenetics and 2) Microbiome Theory and Mechanisms (MTM). The URoL Big Idea seeks to create a new paradigm at the convergence of science, engineering, and technology that will elucidate theoretical frameworks (rules) to enable prediction of the diversity of evolutionary solutions that biological systems use to support life processes seen across the planet. The National Science Foundation has recently invested $36 million in the first projects under the URoL portfolio from two separate solicitations and across more than thirty institutions.

The Epigenetics and MTM opportunities represent a collaboration across Directorates and Offices within the National Science Foundation. Specifically, Epigenetics intends to enable innovative research and promote multidisciplinary education and workforce training in the broad area of epigenetics, while MTM aims to understand and establish theory and mechanisms that govern the structure and function of microbiomes.

Integrative perspectives and research approaches from more than one research discipline are welcomed, as this is a cross-Directorate effort. The interdisciplinary scope of both programs aims to provide unique training and outreach opportunities to train the next generation of scientists in a diversity of scientific approaches and to engage society more generally.

Both programs offer two submission tracks:

  • Track 1 – for projects with a total budget of up to $500,000 and an award duration of up to 3 years, and
  • Track 2 – for projects with a total budget of up to $3,000,000 and award duration of up to 5 years.

For complete details on deadlines and submission guidelines, refer to the Epigenetics program website or contact the Epigenetics Team (epigen@nsf.gov), and the MTM program website or the MTM Team (microbiome@nsf.gov).

BIO looks forward to continuing working on this cross-Directorate venture.

Sincerely,
Image of the signature of Dr. Joanne Tornow, Assistant Director for Biological Sciences
Joanne Tornow, PhD
Assistant Director for Biological Sciences

Share your Input on Cyberinfrastructure

NSF recently released a Dear Colleague Letter (DCL) inviting the community to provide input on data-intensive science and engineering research questions and challenges and the essential data-related cyberinfrastructure (CI) services and capabilities needed to publish, discover, transport, manage and process data in secure, performant and scalable ways to enable that data-intensive research.

This is an opportunity for the BIO community to provide input on questions, challenges and associated needs specifically related to data-focused CI. While this DCL is not a funding opportunity, all input would be used to inform the refinement of NSF’s CI investment strategy and planning of future NSF funding opportunities.

For more information on how to submit ideas, please refer to the DCL (NSF 20-015) or contact the NSF Office of Advanced Cyberinfrastructure, nsfdatacirfi@nsf.gov.

The deadline for submissions is December 16, 2019.

INCLUDES Virtual Office Hour

Please join us for the upcoming information session on the Inclusion Across the Nation of Communities of Learners of Underrepresented Discoverers in Engineering and Science (NSF INCLUDES) program on October 17th, 2019 from 1pm-2pm EST!

During this Virtual Office Hour, program directors from the NSF INCLUDES Implementation Team will discuss the program’s history and new planning grants solicitation (NSF 19-600). Following the discussion, program directors from NSF INCLUDES and the Division of Integrative Organismal Systems (IOS) will answer questions from attendees during an open question and answer period.

Join us remotely and bring questions, comments and concerns! Please use the registration link below to register for our October 17th Virtual Office Hour.

Click here to register

NSF INCLUDES is one of the 10 Big Ideas and is a comprehensive national initiative to enhance U.S. leadership in STEM discoveries and innovations focused on NSF’s commitment to diversity, inclusion and broadening participation in these fields. These planning grants support efforts necessary to build capacity to establish future centers, alliances or other large-scale networks endeavoring to address a broadening participation challenge in STEM at scale.

The first deadline for full proposals is December 3, 2019.

For more details, refer to the full solicitation: NSF 19-600