In 2016, NSF Director France Córdova unveiled ten “Big Ideas” to shape NSF’s priorities for investment at the frontiers of science and engineering, and drive American science into the future. One in particular – “Understanding the Rules of Life” – has reshaped how we at the BIO Directorate think about scientific inquiry in the biological sciences. The Rules of Life Big Idea seeks discoveries that will allow us to accurately predict change and outcomes in biological systems, and to develop infrastructure and innovative tools to help us ask more complex questions than ever before.
NSF has now published a Dear Colleague Letter (“DCL”; NSF 18-031) catalyzed by this Big Idea, titled, “Rules of Life: Forecasting and Emergence in Living Systems.” This DCL solicits research proposals to develop a better understanding of complex interactions within biological systems, and identify causal, predictive relationships across scales, levels of organization and layers of complexity – so-called “rules” for how life functions.
This DCL describes an initial opportunity to identify areas where such rules may exist, to drive progress toward their discovery, and to focus efforts on using these rules for prediction and design of biological systems. Activities supported through this DCL include conferences, EArly-concept Grants for Exploratory Research (EAGERs) and Research Advanced by Interdisciplinary Science and Engineering (RAISE) grants to create opportunities for enabling predictive capability.
As shared by OSTP, “Microbiomes are the communities of microorganisms that live on or in people, plants, soil, oceans, and the atmosphere. Microbiomes maintain healthy function of these diverse ecosystems, influencing human health, climate change, food security, and other factors. The NMI aims to advance understanding of microbiomes to aid in the development of useful applications in areas such as health care, food production, and environmental restoration.”
To kick off the NMI, OSTP hosted an event at the White House to hear from community and research leaders about microbiome science, and opportunities for collaboration and progress. The National Science Foundation’s (NSF) Assistant Director for the Directorate for Biological Sciences (BIO), Dr. Jim Olds, participated in the event as a member of a federal agency panel.
Dr. Olds was proud to announce NSF’s participation in this initiative through a Dear Colleague Letter (NSF 16-087) highlighting NSF BIO’s vision and approach to support and encourage microbiome research across the phylogenetic spectrum and biological scales; from host – microbe interactions to ecosystems. NSF BIO will also foster the development of a national research infrastructure to support collaborative science on microbiomes.
NSF BIO encourages proposals that advance discovery in the realm of microbiomes with support through several programs in fiscal year 2017. These programs cross the entire BIO Directorate and span basic science through translational research that addresses pressing global challenges and support the development of tools needed for the 21st century.
To learn more about NSF BIO’s participation in the National Microbiome Intiative, access the Dear Colleague Letter here: http://go.usa.gov/cuSMH